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Sergio Aguero is set for a month on the sidelines after limping off at White Hart Lane with a hamstring problem. Stevan Jovetic is in the frame to replace the Argentinian after scoring from the bench in Wednesday's win at Spurs, although Manuel Pellegrini is likely to recall Alvaro Negredo alongside Edin Dzeko for the crunch clash with Chelsea. James Milner could be back in contention after a groin problem.
Jose Mourinho seems unlikely to make too many changes at the Etihad but does have options in central midfield, with David Luiz, John Obi Mikel, Nemanja Matic, Ramires and Frank Lampard vying for a place in the starting XI. Mohamed Salah could be included in Chelsea's squad for the first time since joining from Basel.