St. Mary's Stadium
• Southampton have thrown away more points from winning positions in home games than any other Premier League team this season (9).
• Reading have thrown away more points from winning positions on the road than any other side this season (10) and the most overall (17).
Nigel Adkins is expected to name an unchanged side from the one that lost narrowly to Liverpool last weekend. Gaston Ramirez will return to the squad after being given time off on compassionate leave during the week and despite a lack of training, is expected to retain his place behind Rickie Lambert.
P Gazzaniga • N Clyne, J Fonte, M Yoshida, L Shaw • J Cork, M Schneiderlin • J Puncheon, G Ramirez, A Lallana • R Lambert
Danny Guthrie is nearing a return to action after a thigh injury, but his apparent falling out with Brian McDermott may delay any comeback, while both Pavel Pogrebnyak and Jimmy Kebe are doubtful. Kebe's possible absence should see Hal Robson-Kanu continue on the right wing, while Chris Gunter is expected to miss out again, affording Shaun Cummings another chance to impress at right-back.
A Federici • S Cummings, A Mariappa, S Morrison, N Shorey • H Robson-Kanu, J Tabb, M Leigertwood, J McAnuff • J Roberts, A le Fondre