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Manchester United captain Nemanja Vidic, who has announced he will leave the club at the end of the season, is available after suspension. He could replace Jonny Evans, who is out with a calf strain, although fellow defender Phil Jones is available. After a two-month layoff with wrist and back problems, Marouane Fellaini has been ruled out for a further week after injuring his groin in training.
Fulham's record signing Kostas Mitroglou is likely to make his debut, either from the start or off the bench. Lewis Holtby and William Kvist are eligible having been cup-tied in midweek and defender Johnny Heitinga could be in line for his first start following his arrival from Everton.