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Arsenal have serious problems in defence, with Koscielny, Chambers and Monreal all out. Hector Bellerin should start at right-back and Mathieu Debuchy will have to fill in at centre-back. Aaron Ramsey was withdrawn at half time against Galatasaray in midweek and it was confirmed on Friday that he will miss out. Mathieu Flamini also came off but should be okay to play, while Tomas Rosicky has also been ruled out. There have been calls for Lukas Podolski, who impressed in midweek, to be given a chance, but that is highly unlikely.
Newcastle are even more depleted than their hosts, with Steven Taylor and Moussa Sissoko both joining their vast absentee list through suspension. Fabricio Coloccini has been rated a doubt by Alan Pardew but should make it. Ayoze Perez could start in behind last week's hero Papiss Demba Cissé up front.